QUERCIVOROL AS A LURE FOR THE POLYPHAGOUS AND KUROSHIO SHOT HOLE BORERS, EUWALLACEA SPP. NR. FORNICATUS (COLEOPTERA: SCOLYTINAE), VECTORS OF FUSARIUM DIEBACK

Quercivorol as a lure for the polyphagous and Kuroshio shot hole borers, Euwallacea spp. nr. fornicatus (Coleoptera: Scolytinae), vectors of Fusarium dieback

The polyphagous shot hole borer and Kuroshio shot hole borer, two members of the Euwallacea fornicatus species complex (Coleoptera: Curculionidae: Scolytinae), are invasive ambrosia beetles that harbor distinct species of Fusarium harry potter magsafe case fungal symbionts.Together with the damage caused by gallery construction, these two phytopath

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Succinate dehydrogenase deficiency-driven succinate accumulation induces drug resistance in acute myeloid leukemia via ubiquitin-cullin regulation

Abstract Drug resistance is vital for the poor prognosis of acute myeloid leukemia (AML) patients, but the underlying mechanism remains poorly understood.Given the unique microenvironment of bone marrow, we reasoned that drug resistance of AML might rely on distinct metabolic processes.Here, we identify succinate dehydrogenase (SDH) deficiency and

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Paeonol inhibits the Glycolysis in oral squamous cell carcinoma though suppressing NAT10-mediated ac4C modification

Abstract Background Oral squamous cell carcinoma (OSCC) is the most common malignant tumor of the oral and maxillofacial regions.Paeonol, derived from Moutan Cortex, has diverse pharmacological effects including anti-inflammatory and anticancer activities.The N-acetyltransferase 10 (NAT10)-mediated N4-acetylcytidine (ac4C) modification is a newly d

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